
Elena / Elpis Character Guide
Elena, also known as Elpis, is the mysterious catalyst behind the Rhodes Hill outbreak in Resident Evil Requiem. The player's choice about her determines the final outcome.
| Full Name | Elena |
| Aliases | Elpis, Elena / Elpis |
| Role | Antagonist / Story Catalyst |
| Status | Determinant |
| Location | Elpis Laboratory, Rhodes Hill |
| Affiliation | Elpis / Bioweapon |
| First Appearance | Late Game - Elpis Laboratory |
Elena, also known as Elpis, is the mysterious catalyst behind the events at Rhodes Hill. Uncovering her identity and deciding her fate is central to the game’s final act and endings.
Background
Elena was once a patient or test subject at the Rhodes Hill Care Center. Experiments performed on her led to the creation of Elpis, a bioweapon or mutated entity that is connected to the outbreak. By the time the player reaches the Elpis laboratory, Elena is barely human and her consciousness is merged with the entity.
Key Traits
- Role: Antagonist, tragic figure, final choice catalyst
- First Appearance: Late game in the Elpis Laboratory
- Connection: Linked to Grace’s past and the origin of the outbreak
- Entity: Elpis is the bioweapon manifestation of Elena
Story Role
The final choice of the game revolves around Elena / Elpis. The player must decide whether to release her, believing she can be saved, or destroy her to end the threat. This decision, combined with whether Emily survived, determines which ending the player sees.
Key Choices
- Release Elena: Triggers one ending path where Elpis escapes into the world.
- Destroy Elpis: Leads to an alternate outcome where the facility collapses but the threat is ended.
These decisions, combined with whether Emily survives, shape the game’s conclusion.
Notable Details
- Audio logs and research files in the underground lab reveal Elena’s history.
- Her relationship to Grace is hinted at throughout the game through files and cutscenes.
- The name “Elpis” is likely a reference to the Greek spirit of hope, adding a tragic layer to her story.
Visual Guide

Elena was a patient or test subject at the care center before the outbreak.
Experiments on Elena created Elpis, a bioweapon merged with her consciousness.
Elpis becomes the source of the mutations at Rhodes Hill.
Grace and Leon must decide whether to release Elena or destroy Elpis.
The final choice about Elena / Elpis determines whether Elpis escapes into the world or is destroyed. This decision, combined with Emily's fate, produces the game's endings.
Frequently Asked Questions
Who is Elena / Elpis in Resident Evil Requiem?
Elena, also called Elpis, is the mysterious catalyst behind the Rhodes Hill outbreak. She was a patient transformed into a bioweapon whose consciousness is merged with Elpis.
What is Elpis in Resident Evil Requiem?
Elpis is the bioweapon manifestation of Elena. It is connected to the origin of the outbreak and is the focus of the game's final choice.
What is the relationship between Elena and Grace?
Elena has a mysterious past connection to Grace. The final act reveals that Grace's choices about Elpis will determine the outcome of the story.
Should I release Elena or destroy Elpis?
Destroying Elpis is generally considered the safer choice that prevents the bioweapon from escaping, though the best ending also requires saving Emily.
About This Character Guide
This Elena / Elpis character guide is part of the Requiem Guide character database. We document character roles, relationships, story arcs, and ending connections to help players and lore fans understand the people of Resident Evil Requiem.
For the full story, visit the Story Guide and Ending Explained pages. For gameplay help, check the Boss Guides and Weapons Database.
Related Characters
Emily
Emily is a young survivor in Resident Evil Requiem. Her bond with Grace and her fate are central to the story and determine which ending the player sees.

Grace Ashcroft
Grace Ashcroft is the main protagonist of Resident Evil Requiem. She awakens in the Rhodes Hill Care Center with no memory and uncovers her connection to the outbreak.
Leon S. Kennedy
Leon S. Kennedy is a veteran government agent and playable character in Resident Evil Requiem. He arrives at Rhodes Hill to investigate the outbreak and fights alongside Grace.