A curated list of Resident Evil Requiem secrets, unlockable weapons, hidden collectibles, safe codes, optional puzzles, and the ending conditions that reward thorough exploration.
Kotetsu Unbreakable Melee Weapon
Complete the main campaign to unlock the Kotetsu, an unbreakable post-game melee weapon. It usually appears in the item box during New Game+ or challenge runs.
Hidden Safe Codes & Optional Rewards
Safes scattered through the facility contain handgun ammo, healing items, crafting materials and collectible charms. The combination is always hidden in a nearby memo, note or environmental clue.
Quartz Key Secrets
Three Quartz pieces — including the Moon Quartz — are hidden across the Care Center. Collecting all three opens the Central Hall door and unlocks the path to the Courtyard.
Blood Analyzer Crafting Unlocks
Optional Blood Analyzer puzzles in the Blood Lab unlock powerful healing recipes and late-game ammo recipes. Skipping them makes the final chapters harder.
Emily Save Route
Elpis Final Choice
Check Every File
Files, memos and sticky notes often hide safe combinations, key codes, and lore hints. Read every document in a room before moving on.
Explore Optional Rooms
Hidden rooms and backtracking paths contain extra ammo, herbs, charms, and collectible files. Many are locked behind optional keys.
Save Before Endgame
Create a manual save before the final Elpis choice and Emily sequence to unlock all endings without replaying the entire campaign.
Replay for New Game+
Post-game unlocks like the Kotetsu are designed for New Game+ or challenge runs. Use them to clear higher difficulties or speed-run chapters.
Beyond unlockables, Resident Evil Requiem hides several callbacks to classic Resident Evil lore. Keep an eye out for:
- Classic Resident Evil-style typewriter and item box callbacks hidden in safe rooms.
- Environmental notes reference Spencer Mansion and Raccoon City incidents.
- The name "Elpis" mirrors the Greek myth of Pandora's box, tying into the outbreak theme.
Kotetsu Weapon Guide
Stats, unlock method and best use cases for the unbreakable post-game melee weapon.
Endings Explained
All four endings, the true ending route, and how Emily and Elpis shape the final outcome.
Safe Codes
How to find every safe combination and what rewards to expect inside.
Blood Analyzer
Optional logic puzzles that unlock powerful late-game crafting recipes.
Frequently Asked Questions
What are the best Resident Evil Requiem secrets to find?
Top priorities include the Kotetsu unlockable weapon, all safe codes for extra supplies, the optional Blood Analyzer crafting recipes, and the collectible files that explain the Elpis lore.
How do you unlock the Kotetsu in Resident Evil Requiem?
The Kotetsu is unlocked after completing the main campaign. It typically appears in the item box for New Game+ or challenge mode runs, giving you an unbreakable melee weapon.
Are safes worth opening in Resident Evil Requiem?
Yes. Safes contain valuable resources such as handgun ammo, healing items, gunpowder, and collectible charms. The code is always hidden nearby, so check every document.
What determines the endings in Resident Evil Requiem?
Endings are determined by two main factors: whether Emily survives the Research Wing and whether you choose to release or destroy Elpis at the final decision point.
Where can I find the Moon Quartz?
The Moon Quartz is one of three Quartz pieces required to open the Central Hall door. It is found in the Chairman's Office on the second floor of the West Wing.