Resident Evil Requiem Chapter 5 Walkthrough
The party descends into the underground labs to discover Elpis and the truth behind the Rhodes Hill outbreak.
Chapter Overview
This Resident Evil Requiem Chapter 5 walkthrough covers the complete story route, important items, puzzle solutions, enemy encounters and hidden secrets. Use the stats and table of contents below to navigate quickly.
Chapter 5 reveals the truth behind the outbreak as the group descends into the underground research facility. The narrative branches based on whether Emily survived the earlier chapters.
Objectives
- Explore the Blood Lab and solve the Blood Analyzer puzzles.
- Obtain the Level 3 Wristband.
- Survive the underground facility’s tougher enemies.
- Confront Emily’s fate.
- Learn about Elena / Elpis and the experiments that created the outbreak.
Step-by-Step Walkthrough
1. Underground Entrance
After the courtyard rendezvous, Leon and Grace descend into the facility through a hidden elevator. The underground area is heavily populated with advanced infected and a new enemy type that can crawl on walls.
2. Blood Lab and Analyzer Puzzles
The Blood Lab contains two optional Blood Analyzer puzzles:
- Denatured Blood: Click the central node. Reward: Handgun Ammo + Hemolytic Injector crafting recipe.
- Reversible Blood: Follow the path Bottom-left → Middle → Top-right → 2nd from top. Reward: Steroids + crafting recipe.
These puzzles are optional but provide valuable crafting unlocks and resources.
3. Level 3 Wristband
The Level 3 Wristband is required to open the secure research wing. Find it in the locker room near the security checkpoint. This wristband also opens several optional storage rooms containing high-tier ammo and healing items.
4. Emily’s Fate
This is the major branching point of the chapter. If Emily was kept alive and protected, she remains with the group. If she was harmed or left behind in earlier chapters, she mutates and becomes a boss fight for Leon.
- If Emily survives: She helps open the final door to the Elpis laboratory.
- If Emily transforms: Leon must fight Emily (Transformed). See the boss guide for strategy.
5. The Elpis Laboratory
The final area of the chapter reveals Elena, also known as Elpis. Listen to the audio logs and read the research files to understand the experiments. The chapter ends with a choice that sets up the final act.
Key Tips
- The Blood Analyzer puzzles are optional but rewarding.
- If Emily is still alive, protect her in the research wing; losing her here locks the “Save Emily” ending.
- Stock up on healing and magnum ammo before the next chapter.
- Read the research files for lore on Elpis and the outbreak origin.
Next Chapter
Continue to Chapter 6: Final Hour for the endgame, final boss, and branching endings.
Puzzle Solutions
Need help solving this puzzle? Follow the steps below or view the detailed solution page.
- Found in Blood Lab, Underground Facility
- Reward: Handgun Ammo, Steroids, crafting recipes
- Check the detailed solution for step-by-step input.
Emily Transformed
- Study the boss attack patterns before committing ammo.
- Use the recommended weapon to exploit its weakness.
- Keep distance and manage healing items carefully.
Frequently Asked Questions
How long does Chapter 5 take?
Chapter 5 takes about 2 to 2.5 hours. It includes the Blood Lab, Blood Analyzer puzzles, and a major branching decision.
Where is the Level 3 Wristband?
The Level 3 Wristband is in the locker room near the security checkpoint. It opens the secure research wing and several optional storage rooms.
What happens if Emily dies in Chapter 5?
If Emily is harmed or left behind earlier, she transforms into a boss in Chapter 5. Keeping her alive is required for the Save Emily ending.