Blister Borne
Complete Blister Borne boss guide for Resident Evil Requiem: church location, orange cyst weakness, attack patterns, best weapons, and step-by-step strategy.
Church grounds
High
Orange cysts
MSBG 500 / Requiem
Church exit / story progression
The Blister Borne is a grotesque, spiny mutant that Leon fights shortly after meeting Grace and Emily at the church. Its body is covered in pulsing orange cysts that serve as its primary weak points.
Overview
The Blister Borne is a mid-sized boss with high mobility and a disturbing design. It relies on quick lunges and projectile attacks, making it important to keep your distance while targeting its cysts. The fight takes place in the church courtyard, which provides enough space to circle the boss but little cover.
Reward
Defeating the Blister Borne unlocks the church exit and allows Leon, Grace, and Emily to continue toward the Care Center.
Visual Guide
The Blister Borne leaps a short distance toward Leon.
It spews a corrosive projectile in a straight line.
It rears up and slams the ground, creating a shockwave.
Damaged cysts explode and release a poison cloud.
Equip the right weapon
Bring the MSBG 500 shotgun or Requiem rifle before the fight starts.
Aim for orange cysts
Each cyst on the torso and limbs is a weak point. Focus fire on one cyst at a time.
Trigger stagger
Popping a cyst causes the boss to stagger. Unload into the exposed area.
Circle the courtyard
Keep moving in a circle to avoid lunge and acid spit. Use pillars to break line of sight.
Save heavy ammo for the final phase
The Blister Borne becomes faster in the last phase. Use your strongest ammunition then.
- The church has limited cover; use pillars to block Acid Spit.
- Don't waste handgun ammo on body shots; only cyst damage matters.
- Check crates near the church entrance for a shotgun shell resupply.
- Poison cloud lingers after Cyst Burst; reposition before the next cyst.
Frequently Asked Questions
What is the Blister Borne weakness?
The orange cysts covering its body are the weak points. Shooting them causes explosions and staggers the boss.
What is the best weapon against Blister Borne?
The MSBG 500 shotgun or the Requiem rifle are ideal for popping cysts quickly.
Where does the Blister Borne fight take place?
The fight occurs on the church grounds after Leon meets Grace and Emily.
How do you dodge the Blister Borne lunge?
Dodge sideways as it leaves the ground. The lunge has a short wind-up so stay ready.
About This Boss Guide
This Blister Borne boss guide is part of the Requiem Guide database. We test each boss on multiple difficulties to record accurate attack patterns, weaknesses, and weapon recommendations.
For the full chapter context, check the linked walkthrough. For weapon stats and locations, visit the weapons guide.
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