Boss Loadouts

Best Weapons Against Resident Evil Requiem Bosses

Best weapons for every Resident Evil Requiem boss: shotguns, rifles, magnums, and special tools ranked by boss matchup and strategy.

Weapon Matchups by Boss

Best Weapon
Requiem / Magnum
Weakness
Head and exposed core
Location
Late-game facility area

How to beat Emily Transformed in Resident Evil Requiem: late-game facility location, head and core weakness, attack patterns, best weapons like Requiem rifle and Magnum, and ending impact.

Best Weapon
Flashlight / S&S M232
Weakness
Light sources
Location
Rhodes Hill Care Center - Water Treatment Plant

How to beat the Shadow Ghost (The Girl) in Resident Evil Requiem: Water Treatment Plant location, light weakness, attack patterns, best weapon S&S M232, and step-by-step strategy.

Best Weapon
MSBG 500 / Requiem
Weakness
Orange cysts
Location
Church grounds

How to beat Blister Borne in Resident Evil Requiem: church location, orange cyst weakness, attack patterns, best weapons like MSBG 500 and Requiem rifle, and step-by-step boss strategy.

Best Weapon
MSBG 500 Shotgun
Weakness
Headshots and explosive damage
Location
Rhodes Hill Care Center - Kitchen/Cafeteria

How to beat Chunk in Resident Evil Requiem: kitchen location, headshot weakness, attack patterns, best weapons like the MSBG 500 shotgun, and step-by-step boss strategy.

Best Weapon
Requiem / Explosive rounds
Weakness
Eyes and abdomen
Location
Underground / Sewer facility

How to beat Titan Spinner in Resident Evil Requiem: sewer location, eye and abdomen weakness, attack patterns, best weapons like Requiem rifle and explosive rounds, and strategy.

Weapon Guides